Equally effective for all Stage I tumors, regardless of age and site, are external beam radiation therapy and intracavitary or interstitial radiation therapy. Smaller lesions are sometimes treated with only intracavitary or interstitial radiation therapy.

Five-Year Survival  70 to 80 percent 

Investigational 
• Meticulous surgical staging before radiation therapy.
• Chemotherapy given simultaneously with radiation therapy. Chemotherapeutic regimens under investigation 
  include mitomycin-C + 5-fluorouracil (5-FU) with or without cisplatin .
• Radiation therapy with heat (hyperthermia).

Stage II (squamous cell carcinoma and adenocarcinoma)
TNM T2, N0, M0 
The carcinoma involves the adjacent vaginal tissue but has not extended to the pelvic wall.

Standard Treatment  External beam radiation and interstitial or intracavitary radiation.
Five-Year Survival About 50 percent